可是N从未抛弃证帝诸天过努许风顾奕南力，参与各种有意义的科研实习，使用暑假在复旦大学的药理试验室，学习乳鼠心肌细胞的培育、日本秘戏图转染、ELISA KIT、PCR、Western blot等技能添加自己的实践阅历。后来针对硕博混申的战略，咱们最终有针对性的创造PS。最终托福101 GRE1290 成功拿到了University of Pittsburgh 药剂学博士的选取。
“Curiosity killed the cat” is an expression that everyone has heard of, but not many people know the second part - “Satisfaction brought it back”. I like the proverbs. It is because our curiosity has万重利 led to so many inventions and discoveries which advance 正月初六,包凡一美国研究生恳求匹兹堡药剂学博士PS,颈椎牵引our world today.
My curiosity to the life sciences starts when I learned that my high school mathematics teacher suffered from breast carcinoma, and I found that tumors are not far away from our daily life. The Ministry of Health of China reported that tumor has become the first cause of death in China now. I start to think and also wish to develop effective drug medicines that can cure the cancer patients and also help them to survive in the battle by defeating tumors with fewer risks and costs. I am very curious about tumors/cancer biology and how to cure and prevent them. That has motivated me to select and to study Pharmacy drug design and discovery research programs at university. I seek to continue my exploration research so that I can dedicate my knowledge and apply what I 宠物老友记have learned in class to discovering alternative solutions or “golden keys” that will free us from suffering tumor. To achieve my goal and begin my research career to designnagitive better medicine to conquer the malignant diseases, I strongly believe that I need to further enrich and master my scientific knowledge in drug design and pharmacology, improve my experimental skills and learn a new way of thinking and research studies. Therefore, to study Medicinal Chemistry drug design at the University of Pittsburgh seems like 高泰宇和黄靖翔闹掰了a natural fit.
I'm currently a senior student studying for a BS in Pharmacy at Tongji Medical College, Huazhong University of Science and Technology，which is ranked top 10 in China, among the first Universities joining the national “211 Project” and “985 Project长春吉康”. I have taken and studied Pharmaceut高木斗ical Chemistry, Pharmaceutics an正月初六,包凡一美国研究生恳求匹兹堡药剂学博士PS,颈椎牵引d Pharmacology, etc. I trust that these core courses have given me a solid foundation to continue my pos正月初六,包凡一美国研究生恳求匹兹堡药剂学博士PS,颈椎牵引tgraduate study of Medicinal Chemistry at the University of Pittsburgh.
I am highly interested in the practical lab w伦理片97影视网ork. I was honored to be a group leader in my second year of studies to lead the preparation of angelica polysaccharide oral liquid solution. Angelica is a traditional Chinese medicine for treating anemia. Angelica polysaccharide is its main ingredient and can reduce anemia effectively and strengthen the body's immunity.
At the beginning of the experiments, our professor advised us to use the method of alkali precipitating-acid extracting. This method has been used in the laboratories for several ye钱庄血案ars. However, the result was disappointing. A large amount of precipitations often appeared in one month later and the content of polysaccharide decreased, which resulted in the loss of active ingredient. After ex黑月之王和苍碧之月的公主tensive research I found that ZTC can elucidate Gallotannicacid, protein and lymphatic temperament. I worked very hard with my team and started a new experiment with ZTC as clarificant to extract angelica polysaccharide. The result was very exciting because the oral liquid was steady without precipitation. This improved method is also cheaper to setup and easy to use. The outcome could produce a sufficient amount of polysaccharide.
Based on the success of this experiment, I was co-author in a in a research publi李嘉臣微博cation, titled ‘The Pharmacological Effects and Research Progress of Angelica Polysaccharide' in the Chin正月初六,包凡一美国研究生恳求匹兹堡药剂学博士PS,颈椎牵引a Journal of Modern Medicine (2012). As briefed in abstract of the article, “Angelica polysaccharides have good medical value for anti-tumor, regulation of the immune system, promotion of hematopoietic function. The development of pharmaceutical preparations and complex pharmaceutical preparations of Angelica polysaccharide has a wide range of applications. This paper summarizes the pharmacological effects of angelica polysaccharide and research progress through articles and researches”.
Besides my academic studies and lab research, I still actively seek summer interns in order to understand how my studies can be applied in the real world.
In the summer of 2012, I worked as an intern in the Drug Formulation Department at WuXi AppTec Co Ltd (www.wuxiapptec.com), which is a leading global CRO company producing pharmaceutical, biopharmaceutical, and medical device with operations in China and the United States. During my internship, the team was working on designing a sustained-release tablet for an antidepressant medication. I worked with the team and senior scientists and learned wet granulation, drying, mixing, tabletting and coating. Such excellent working environments also trained me familiar with several modern equipment, including TAP density, screening instrument and tablet press, coating machine, vibrating fluidizedbed dryer, three dimensional motions mixer and granulator. This intern experience enabled me to understand multinational company culture and requirement, including tight quality control, diligence with test procedures, and many new skills that I hadn't come across at university.
In addition, I also obtained summer internship at Fudan University School of Pharmacy on weekends in last summer. Basically, in 7 days a week, I worked in the pharmacology laboratory and was fascinated by all the experiments, including Elisa kit, western blot, PCR, isolating the neonatal rat cardiac fibroblasts from the heart, cell culture and transfection. I have worked under senior Postdoc fellows and learned to transfect siRNA with liposome into the neonata正月初六,包凡一美国研究生恳求匹兹堡药剂学博士PS,颈椎牵引l rat cardiac fibroblasts, then cultivated the cells, and measured the protein expression and transformation of RNA by PCR and western blot.
2012 Noble Chemistry prize goe华能生长宝s to Dr. Brian Kobilka for his outstanding contribution in GPCRs structure and function research. By reading research articles, I learned that G protein coupled receptors (GPCRs) play a key role in signal recognition and cellular communication, making them important therapeutic targets. CB2 receptors申必达, as a member of GPCRs involving immune signal transduction, are crucial for understanding its mechanism of action and target-based drug design. I am interested in CB2 receptors and I believe that they will constitute a challenging area in drug design and discovery. I am also fascinating about DNA damaging mechanism studies and novel DNA damaging anticancer drug design discovery, as well as the Mass Spectrometry-based biological evaluations, metabolite identification, and discovery and structure elucidation of biomarkers of effect or predisposition. During the process of the research investigation, many multidisciplinary skills and training are involved. I can learn how to combine all kinds of elements into consideration and operate a whole program. This experience will help me have a better understanding of pharmacy/pharmaceuticals and improve my practical skills.
With my industrial a姐姐莲限免nd acade国外天体mic interns, I have gained a great of experience in research study and industrial working experi水稀ence. Thus, I 正月初六,包凡一美国研究生恳求匹兹堡药剂学博士PS,颈椎牵引am looking forward to my post正月初六,包凡一美国研究生恳求匹兹堡药剂学博士PS,颈椎牵引graduate studies abroad. Undoubtedly, I will continue my academic research in US to fulfill my dream for curing the patients and the healthcare c拍痧拍出紫疙瘩ause. Faced up with the challenges and difficulties on the road, I will make good plan of study and work very hard on my best toward my scientific career development to make my “curiosity” dreams come to true.